Mu mutobe wigifu wabantu, BPC 157 ihagaze neza mumasaha arenga 24, bityo ikagira bioavailable yo mumunwa (burigihe itangwa wenyine) ningaruka zingirakamaro mumitsi yose yigifu.Iri ni itandukaniro rikomeye nizindi peptide zujuje ubuziranenge, zishingiye ku mikorere y’inyongera y’abatwara cyangwa zangirika mu buryo butemewe mu mutobe w’igifu wa muntu. Kubera iyo mpamvu, BPC 157 ihamye irasabwa kuba umuhuza wa cytoprotection ya Robert, ikomeza ubusugire bwa ogastrointestinal mucosa.Turasaba ko uruhare rwa BPC 157 muri cytoprotection ya Robert - ni ukuvuga ubushobozi bwo kurwanya ibisebe byatewe na alcool biterwa na gastric, ibyo Robert yise cytoprotection - hamwe nubushobozi bwo kurwanya ibisebe bituruka ku guhura gukabije n’umukozi w’ubumara na selire. byerekana isano iri hagati yinda nubwonko bwubwonko.
Perovic yatangaje ko BPC 157 ifite ingaruka zikomeye zo kuvura zijyanye no gukira kw'imbeba zifite igikomere cy'umugongo hamwe no kumugara umurizo (gukomeretsa umunota 1 wo gukomeretsa umugongo wa sacrocaudal [S2 - Co1]).By'umwihariko, ubuyobozi bumwe bwa intraperitoneal BPC 157 muminota 10 nyuma yimvune irwanya ingaruka mbi.Ibinyuranye, gukomeretsa k'umugongo no kumugara umurizo bikomeza mu mbeba zitavuwe, zisuzumwa iminsi, ibyumweru, ukwezi, n'umwaka nyuma yo gukomereka.Icyitonderwa, BPC 157 yerekana ibyangiritse bikunze kwangirika.Kubwibyo, BPC 157 ivura ibisubizo bigaragara mubikorwa, microscopique, na electrophysiologic gukira.
Icyitonderwa, mu mbeba zifite igikomere cyumugongo, habaho reperfusion ihoraho.BPC 157 imaze gukomeretsa iminota 10 nyuma yo gukomeretsa nyuma yo kwikomeretsa, habaho kurindwa guhoraho kandi nta mvururu zatewe n’umugongo zatewe no guhungabana zongeye kugaragara.Imvune zose z’umugongo zihita zitera kuva amaraso, hamwe n’urupfu rwa neuron na oligodendrocytes.
Kubwibyo, birashoboka ko Hemostasis yo hambere ishobora kuba ingirakamaro kandi igafasha gukira nyuma yumugongo wumugongo.Nyamara, ingaruka zakozwe na BPC 157 zishobora kuba zitandukanye ningaruka zoroheje zo kuvura indwara zitera uruti rwumugongo, kubera ko BPC 157 nayo itezimbere kuburyo bugaragara imikorere ya trombocyte mu mbeba itagize ingaruka kumpamvu ziterwa na coagulation.Mugihe cyo gukira imvune yumugongo, BPC 157 nayo irinda byimazeyo endotelium, igabanya imvururu zifata imitsi ya periferique, igahita ikora inzira zinyuranye zambukiranya inzira, kandi ikarwanya syndromes iterwa no gufunga imitsi.Rero, tuvuze ko hari uruhare runini rwimitsi itera kwikuramo umugongo, birashoboka ko umuvuduko wamaraso wongeye gushyirwaho wahujwe na BPC 157 nta gushidikanya ko wagira uruhare mugukiza vuba.Byongeye kandi, urebye ko BPC 157 iteza imbere burundu nyuma yo kwikuramo uruti rwumugongo, twakagombye kumenya ko iyo BPC 157 itanzwe mugihe cyo kwisubiraho, irwanya indwara yubwonko iterwa no gufatana kwingingo zombi zifata imitsi ya karoti.BPC 157 ikemura ibyangiritse kandi ikabuza kwibuka, lokomoteri, hamwe no guhuza ibihombo.BPC 157 bigaragara ko ikora izi ngaruka muguhindura imvugo ya gene muri hippocampus.
Mu gusoza, BPC 157 igira ingaruka nziza kumitsi, sikizofreniya, no gukomeretsa umugongo.
Abashakashatsi berekanye ko BPC 157 igira ingaruka zitari nke mu mubiri.Ntampamvu yo kwerekana ko inyungu za BPC 157 zigarukira kubikorwa byuburyo bwakoreshejwe hamwe na / cyangwa uburyo bwo kugabanya imipaka.Mubyukuri, turashobora kuvuga ko imikorere, byoroshye gukoreshwa, imiterere yubuvuzi itekanye hamwe nuburyo bwa BPC 157 byerekana ubundi buryo, bushobora gutsinda, icyerekezo kizaza cyo kuvura indwara zifata ubwonko.Kubwibyo, ubushakashatsi bwinyongera burakenewe kugirango dusobanure neza uburyo BPC 157 ishobora kuvura uburyo bwihariye bwo gukora bukubiyemo imbuga nyinshi zidasanzwe muri CNS.Ingaruka kumikorere ya benshi, niba atari yose, sisitemu ya neuronal kurwego rwa molekile, selile, na sisitemu bigomba gushakishwa.Bimwe mu bisubirwamo byisubiramo bya CNS cyangwa ingingo zizenguruka, kamwe mu turere tumwe na tumwe two mu bwonko tudafite inzitizi y’amaraso n'ubwonko, ni inzira izwi aho peptide ikoreshwa na sisitemu ishobora kugira ingaruka nyamukuru.Rero, igomba gukora mu nda-ubwonko, utitaye ko iki gikorwa kiziguye cyangwa kitaziguye.
